A loose tire detached from an eastbound vehicle on Highway 401 near Newtonville Road in Clarington, Ontario, struck a passing SUV and caused significant damage to the windshield and roof. Two occupants of the SUV were injured, with a female passenger sustaining serious injuries and airlifted to a trauma centre, while the other driver sustained minor injuries. The incident led to the westbound lanes being closed and the eastbound lanes initially shut before reopening, disrupting traffic for hours. Investigators say the tire and wheel assembly detached from the eastbound vehicle, and the driver has been charged over detached parts. Video and photos from the scene showed extensive damage to the affected SUV and debris across multiple lanes. Authorities urged drivers to seek alternative routes as the investigation continues.