Africa is a surname. Notable people with the surname include:
Candido Africa (1895–1945), Filipino medical researcher
Coco weAfrica (born 1991), Zimbabwean musician
Dale Africa (born 1981), US Virgin Islands cricketer
John Africa (1931–1985), American activist
J. Simpson Africa (1832–1900), American politician
Keagan Africa (born 1985), South African cricketer
Melrick Africa (born 1978), Namibian rugby union player
Susan Africa (born 1959), Filipino actress
Zayn Africa (born 1994), Nigerian musician