Plot
The ever-glamorous and self-indulgent Edina Monsoon and Patsy Stone are now in their 60s. Edina's PR company is in decline and her attempt to release an autobiography falls through when a publisher rejects the manuscript. While setting up designer Huki Muki's fashion event, Patsy learns that supermodel Kate Moss is looking for a new PR agent, and immediately calls Edina to inform her. Their phone call is overheard by Edina's PR rival Claudia Bing when Edina accidentally leaves her phone on speaker.
Edina and Patsy attend the fashion event with Edina's 13-year-old granddaughter Jane (whom Edina calls "Lola"), while Saffron "Saffy" Monsoon, Edina's daughter and Jane's mother, goes on a date with her new boyfriend Nick. Edina finds Kate Moss on a balcony overlooking the Thames. When both Edina and Claudia attempt to approach Kate, Edina accidentally topples Kate into the river. Among the witnesses is Lulu, one of Edina's remaining clients, who is at odds with Edina after being replaced as a performer at the event.
Hysteria pervades the event as Kate is presumed dead. The media immediately storm the scene to report her disappearance and assumed death. Edina and Patsy, along with Jane, are taken into police custody. Saffy arrives to see them with Nick, who is revealed to be a police detective.
After being released the following day, Edina becomes the target of hate mail and Internet trolls, while Patsy has been fired from her job because of her association with Edina. At night, the pair take a boat to the Thames to search for Kate's body, using Edina's personal assistant Bubble as a searching device, but she disappears into the water. They decide to flee the country before the media firestorm worsens, taking Jane and her credit card along. The three land in Cannes, while back in London, Saffy desperately searches for Jane, eventually discovering Edina's whereabouts through her stylist, Christopher.
In Cannes, Edina and Patsy try to devise money-making schemes. After Patsy fails to convince a wealthy former lover to marry her, the two happen upon an elderly baroness who is the richest woman in the world. In order to gain access to her fortune, Patsy disguises herself as a man named Pat Stone and flirts with her. The following day, Patsy marries the baroness, granting Edina and Patsy the lavish lifestyle they had been pursuing, as they stay in a luxury hotel with Dame Joan Collins and Dame Edna Everage as fellow guests.
Meanwhile, Emma Bunton, who saw Edina and Patsy in public, tells Lulu about their whereabouts. Lulu flies out to Cannes and meets with Bubble, who is alive and has bought a massive Cannes pavilion after embezzling money from Edina's company for years. Saffy arrives in Cannes with Nick and immediately heads to the hotel to find Jane, who is with Emma.
A vengeful Lulu reports Edina and Patsy's location to the police. The police find Edina and Patsy and chase them through the town, the duo escaping in a hijacked three-wheeled delivery van. As they reach Bubble's pavilion, the van's brakes fail and they roll backwards and fall into an infinity pool attached to Bubble's house. Saffy arrives at the scene to find Edina and Patsy slowly sinking into the pool, still inside the van. Edina apologises to Saffy for being greedy, self-centred and a neglectful mother. In response, Saffy tells her that she loves her. When Bubble reveals that Kate Moss is alive, Edina immediately exits the van, realising she is innocent.
People all over the world celebrate the fact that Kate Moss is alive. As Kate's new PR, Edina revitalises her own career and finally launches her autobiography, while Kate has been in even more demand since she was found. At Saffy's insistence, Patsy reluctantly reveals to the baroness that she is in fact a woman, not a man called Pat. The baroness, in turn, reveals that she is actually a man.