Bruno is a surname.
Alessio Bruno (born 1994) Italian footballer
Andrea Bruno (1931–2025), Italian architect
Angelo Bruno (1911–1980), former boss of the Philadelphia crime family
Chris Bruno (born 1966), actor
Doug Bruno (born 1950), former college basketball player and women's basketball coach
Dylan Bruno (born 1972), American actor
Edoardo Bruno (1928–2020), Italian film critic
Federico Bruno (born 1993), Argentine distance runner
Francesco Bruno (born 1968), Italian sport shooter
Francesco Faà di Bruno (1825–1888), Italian mathematician and priest
Frank Bruno (born 1961), boxer
Gaetano Bruno (born 1973), Italian actor
Gioia Bruno (born 1963), American musician
Giordano Bruno (1548–1600), Italian philosopher, priest, cosmologist and occultist, executed for heresy
Giovanni Bruno (born 1988), Italian footballer
Giuliana Bruno, academic and art writer
Hal Bruno (1928–2011), American journalist
Jahzir Bruno (born 2009), American actor
J. Jon Bruno (1946–2021), Episcopal Bishop of Los Angeles
Joseph Bruno (1929–2020), New York politician
Julio Bruno is a Spanish businessman and former Executive Chairman and CEO of Time Out Group.
Kelly Bruno (born 1984), American runner
Michele Bruno (1941–2016), South African drag queen
Nick Bruno, American film director and animator
Nick Bruno (born 1951), eighth president of the University of Louisiana at Monroe
Oscar Bruno, Argentine-American numerical analyst
Quentin Bruno, singer, dancer and actor
Robert R. Bruno Jr. (1945–2008), American artist, inventor and businessman
Salvatore Bruno (born 1979), Italian football striker
Sébastien Bruno (born 1974), French rugby union player
Tony Bruno (born 1952), American sports talk radio host
Tory Bruno (born 1961), aerospace executive and president and CEO of United Launch Alliance
Fictional characters
Avilio Bruno, in the anime 91 Days
Billi Bruno (born 1997), actress
Giorgio Bruno, in the video game Time Crisis 4
Bruno Airmont, in Shadow Ticket by Thomas Pynchon
