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Catherine Day — latest news, discussion & facts — IJR

Catherine Day

biochemist

Catherine Day

New Zealand biochemist

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About Catherine Day

Catherine Louise Day is a New Zealand biochemist. She is currently a professor and was the head of the biochemistry department at the University of Otago.

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Occupation: biochemist, academic
Position held: full professor
Citizenship: New Zealand

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Facts from Wikidata (CC0). Image via Wikimedia Commons (CC BY 4.0).

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Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins Structural insights into the degradation of Mcl-1 induced by BH3 domains Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans Bak activation for apoptosis involves oligomerization of dimers via their alpha6 helices TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis.Solution structure of prosurvival Mcl-1 and characterization of its binding by proapoptotic BH3-only ligands.University of Otago full professor

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