Marriage and children
Apthorp married Grizzel Eastwicke on 13 January 1726. She was born in Jamaica to Griselda Lloyd and John Eastwicke. A descendant of the couple, great-grandson Joseph Coolidge, stated that: "Her portrait, painted by Sir Peter Lely, and showing her to have been remarkably beautiful, remains in the family." She was said to have "rare qualities of person and character."
Apthorp and his wife had eighteen children, three of whom died before him:
Charles Ward Apthorp (1726 – May 1797) (later of Apthorp Farm). Charles married Mary McEvers. His granddaughter was Maria Eliza Van Den Heuvel, who married John Church Hamilton. His great-granddaughter, Charlotte Augusta Gibbes, married John Jacob Astor III.
Grizzel Apthorp Trecothick (1727 – 1769). She married Barlow Trecothick.
John Apthorp (1730 – 1773). He married 1st Alica Mann, sister of Horace Mann, 2nd Hannah Greenleaf daughter of Stephen Greenleaf, granddaughter of Thomas Loring. He was member of the house of Thomlinson and Trecothink. On a voyage to Charleston, South Carolina, they were lost at sea. Their children survived them, Colonel John T. Apthorp, Hannah who married Charles Bulfinch, and Frances Western who married Charles Vaughn.
James Apthorp (17 November 1731 – 1799).He married Sarah Wentworth. Her family owned Wentworth Manor in Yorkshire.
East Apthorp (27 March 1733 – 20 April 1816), who became a minister. East Apthorp built in 1761 a mansion designed by Peter Harrison; it is now part of the Harvard University campus in Cambridge, Massachusetts.
Susan Apthorp Bulfinch (1734 – 15 February 1814). She married Thomas Bulfinch on 8 October 1754. He was warden of the King's Chapel church after the Revolutionary War. They were the parents of architect Charles Bulfinch.
Ann Apthorp Wheelwright (18 January 1736 – 1814). She married Nathaniel Wheelwright.
Henry Apthorp (19 March 1737 – 1762)
Stephen Apthorp (10 March 1738 – 1774)
Joseph Apthorp (22 April 1739 – March 1749)
Elizabeth Apthorp McEvers Bayard (28 May 1740 – 1800). She was married twice to men from New York: James McEvers (her eldest brother's brother-in-law), and her brother-in-law Robert Bayard, after her sister Rebecca's death.
Thomas Apthorp (19 October 1741 – ?). After his father's death and until 1776, Thomas was made paymaster to British forces. He went to England, married in Lisbon and died in Ludlow, Wales.
Catherine Apthorp I (1742 – 1743). Died young.
George Apthorp (1744). Died young.
Robert Apthorp (1745). Died young.
Rebecca Apthorp Bayard (20 June 1746 – 1771). She married Robert Bayard from New York.
William Henry Apthorp (26 February 1749 – 1781). He married Mary Thompson.
Catherine Apthorp II (1750). She died on the date of her birth.
The family had a home in Boston and another outside town in Quincy, Massachusetts.