2011–present: Focus as a producer and Pixels
As early as 2009, Variety magazine reported that Columbus, Michael Barnathan, and Mark Radcliffe were working on a film adaptation of Kathryn Stockett's novel The Help. Released in 2011, the film of the same name was directed by Tate Taylor with Columbus serving as producer. The film and novel recount the story of a young white aspiring journalist, Eugenia "Skeeter" Phelan, and her relationship with two black maids, Aibileen Clark and Minny Jackson, during the Civil Rights Movement. The film received critical and commercial success, earning $216.6 million worldwide. Roger Ebert described it as "involving and wonderfully acted", and Amy Biancolli of the San Francisco Chronicle called it "a film that makes us root for the good guys, hiss at the bad and convulse in laughter when good wreaks vengeance with a smile". At the 84th Academy Awards, Octavia Spencer won the Academy Award for Best Supporting Actress for her role. The film also received three other nominations: Best Picture, Best Actress and Best Supporting Actress for Jessica Chastain. The film won the Screen Actors Guild Award for Outstanding Performance by a Cast in a Motion Picture.
In 2013, Columbus co-authored the House of Secrets book series with Ned Vizzini. Shortly, Columbus returned to the Percy Jackson series, as an executive producer for the sequel titled Percy Jackson: Sea of Monsters. Directed by Thor Freudenthal, and starring much of the cast from the previous installment, the film grossed $200.9 million worldwide. However, it received a divided critical reaction. Columbus next produced Night at the Museum: Secret of the Tomb, the final installment in the Night at the Museum series. Released in December 2014, the film was a financial success, grossing $363.2 million at the box office. It was also Robin Williams' final film appearance before his death.
In 2014, Columbus cofounded production company Maiden Voyage Pictures with his daughter, Eleanor. He also co-founded an animation studio called ZAG Animation Studios with Saban Capital Group and ZAG Entertainment.
Columbus directed the science fiction comedy Pixels (2015). He first learned about the project from Adam Sandler; Of that encounter, he said, "He gave me the Pixels script after we hit it off. My daughter read it and said, 'You have to read this movie. It's completely fun and unexpected'". The film is based on Patrick Jean's 2010 short film of the same name, which depicts aliens who attack the Earth in the form of arcade video games. Principal photography took three months in Toronto, after which computer-generated imagery and visual effects were then applied. Starring Sandler, Kevin James, Michelle Monaghan, Peter Dinklage, Josh Gad and Brian Cox, Pixels was met with mixed reviews but earned $244.9 million at the box office. Marjorie Baumgarten of The Austin Chronicle said the film is "flat-footed and grows tedious after the first hour" but praised the 3D effects which "enhances the action". Peter Travers of Rolling Stone gave the film one star out of four, calling it "a 3D metaphor for Hollywood's digital assault on our eyes and brains [...] relentless and exhausting".
Also in 2015, Columbus served as a producer for three films: supernatural horror The Witch, Italian drama Mediterranea, and a comedy titled It Had to Be You. During 2016, Columbus produced small-scale and independent features. First, The Young Messiah, a fictional story of a seven-year-old Jesus who tries to discover the truth about his life when he returns to Nazareth from Egypt. Second, Tallulah, a comedy drama starring Elliot Page, Allison Janney, and Tammy Blanchard; the film is about a young woman who takes a baby from its negligent mother and pretends the child is her own. Tallulah premiered at the Sundance Film Festival on January 23, 2016, and was released on Netflix on July 29, 2016. In 2017, Columbus served as an executive producer for Menashe, and a producer for Patti Cake$ and I Kill Giants. Columbus also produced The Christmas Chronicles (2018), a family film directed by Clay Kaytis.
In 2018, Columbus was announced as director of a Five Nights at Freddy's film adaptation, but he backed out of the project by September 2021. In 2019, Columbus joined the producers of The Lighthouse, a film directed by Robert Eggers and starring Willem Dafoe and Robert Pattinson as two lighthouse keepers who lose their sanity. In 2018 it was announced that Columbus would serve as an executive producer for Scoob!, an animated adventure film featuring characters from the Scooby-Doo franchise; it was released on May 15, 2020. He has also directed The Christmas Chronicles 2 (2020), a sequel to the film he had co-produced.
On April 18, 2024, it was announced Columbus would direct a film adaptation of the Richard Osman novel The Thursday Murder Club for Amblin Partners. The movie - with a cast including Helen Mirren, Pierce Brosnan, Ben Kingsley and Celia Imrie - was co-produced by Steven Spielberg and received positive reviews from critics.
Columbus has been attached as a director to a Hello Ghost remake, announced in 2011. In 2017, Columbus said he had written a script for Gremlins 3.
In January 2025, it was reported by Deadline that Columbus was writing sequels to Gremlins and The Goonies for Warner Bros., which were later confirmed by the studio and also will have Steven Spielberg involved as a producer. In November 2025, it was confirmed that Columbus would be co-writing the script along with Zach Lipovsky and Adam Stein and that Columbus would also direct and produce Gremlins 3 replacing director Joe Dante who directed the first two films. Gremlins 3 is currently scheduled for release on November 19, 2027.