Coke is a surname. Notable people with the surname include:
Christopher Coke (born 1969), convicted drug lord in Jamaica
David Coke (1915–1941), British Second World War pilot
Dorothy Coke (1897–1979), British artist
Edward Coke (disambiguation), several people
Giles Coke (born 1986), English footballer
Jānis Čoke (1878–1910), Latvian revolutionary and bank robber
John Coke (disambiguation), several people
John Talbot Coke (1841–1912), British Army major-general
Octavius Coke (1840–1895), American lawyer and politician
Peter Coke (1913–2008), British actor, playwright and artist
Phil Coke (born 1982), American Major League Baseball pitcher
Richard Coke (1829–1897), American lawyer and politician, governor of Texas and United States senator
Richard Coke Jr. (1790–1851), American lawyer and politician, uncle of Octavius and Richard Coke
Richard Toby Coke (born 1954), English politician
Sir Robert Coke, 2nd Baronet (1645–1688), English Member of Parliament in 1685
Roger Sacheverell Coke (1912–1972), English composer and pianist
Thomas Coke (disambiguation), several people
Van Deren Coke (1921–2004), American photographer, scholar and museum professional