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David Baker

bioinformatician

David Baker

American biochemist and computational biologist (born 1962)

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About David Baker

David Baker is an American biochemist and computational biologist who has pioneered methods to design proteins and predict their three-dimensional structures. He is the Henrietta and Aubrey Davis Endowed Professor in Biochemistry, an investigator with the Howard Hughes Medical Institute, and an adjunct professor of genome sciences, bioengineering, chemical engineering, computer science, and physics at the University of Washington. He was awarded the shared 2024 Nobel Prize in Chemistry for his work on computational protein design.

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Occupation: bioinformatician, biochemist, university teacher, computational biologist
Citizenship: United States
Born: October 6, 1962
Website

Facts from Wikidata (CC0). Image by John Sears via Wikimedia Commons (CC BY-SA 4.0).

https://sites.uw.edu/biochemistry/faculty/david-baker/, https://www.bakerlab.org/

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Design of a Novel Globular Protein Fold with Atomic-Level Accuracy Contact order, transition state placement and the refolding rates of single domain proteins.Protein structure prediction and analysis using the Robetta server Assembly of protein tertiary structures from fragments with similar local sequences using simulated annealing and Bayesian scoring functions Kemp elimination catalysts by computational enzyme design Protein-protein docking with simultaneous optimization of rigid-body displacement and side-chain conformations Improving physical realism, stereochemistry, and side-chain accuracy in homology modeling: Four approaches that performed well in CASP8.De novo computational design of retro-aldol enzymes University of Washington University of Washington School of Medicine

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