Doc is an American medical drama television series developed by Barbie Kligman which premiered on January 7, 2025 on Fox and stars Molly Parker in the lead role. It is based on the Italian series Doc – Nelle tue mani (2020–present), which in turn was inspired by the true story of Dr. Pierdante Piccioni, former chief of the emergency room of Lodi and Codogno, who forgot the previous 12 years of his own life following a 2013 car accident.
The series has received mixed reviews from critics.
In March 2026, Fox renewed the series for a third season which is set to premiere on September 22, 2026.
Contents
Premise
Dr. Amy Larsen, the chief of internal medicine at Minneapolis's fictional Westside Hospital, suffers a traumatic brain injury in a car accident that causes her to lose her memory of the last eight years. She struggles to resume her medical career and build a new life after the events she cannot remember, which include a divorce from her husband and a tragedy that made her push others away.
Cast and characters
Main
Molly Parker as Dr. Amy Larsen, attending physician in internal medicine, former Chief of Internal Medicine prior to her accident where she lost the memories of the past eight years
Omar Metwally as Dr. Michael Hamda, Chief Medical Officer, and Amy's ex-husband
Jon Ecker as Dr. Jake Heller, chief resident, and Amy's boyfriend
Amirah Vann as Dr. Gina Walker, a neuropsychiatrist, and Amy's best friend
Anya Banerjee as Dr. Sonya Maitra, a third-year resident, and dating TJ
Patrick Walker as Dr. Theodore "TJ" Coleman (seasons 2–present; recurring season 1), a first-year resident, and dating Sonia
Charlotte Fountain-Jardim as Katie Hamda (season 2; recurring season 1; guest season 3), Amy and Michael's daughter
Felicity Huffman as Dr. Joan Ridley (season 2), new Chief of Internal Medicine and Amy's mentor
Blair Underwood as Dr. Ben Grant (season 3; special guest season 2)
Recurring
Scott Wolf as Dr. Richard Miller, briefly replaced Amy as Chief of Internal Medicine
Sarah Allen as Nora Hamda, Michael's second wife
Claire Armstrong as Nurse Julie Kenner
Conni Miu as Nurse Liz Kwon
Darrin Baker as Max Garner, chairmen of the hospital board
Allan Dobrescu as Darrin Amalia, tech
Emma Pfitzer Price as Hannah Clark (season 2), a new intern whose father used to work under Amy
Daniel Gravelle as Charlie Clark (season 2), Hannah's brother
Samantha Massell as Rachel (season 2), Jake's ex-wife
Barrett Carnahan as Graham Barker (season 3), an new intern who is the son of one Westside's donors
Raffa Virago as Nikki De Silva (season 3), an new intern
Cecilia Lee as Ruth Chen (season 3), an new intern
Kolton Stewart as Kyle Ferguson (season 3), a new intern
Guest
Brian Tee as Bobby Ho (season 2)
Judd Hirsch as Herman Zweig (season 2)
Episodes
Production
Development
On February 16, 2023, Fox announced that it was developing an adaptation of Doc – Nelle tue mani, a series created by Francesco Arlanch and Viola Rispoli for Italian channel Rai 1. On April 3, 2023, it was announced that the adaptation had been picked up for a full series, created by Barbie Kligman, who is also credited as an executive producer alongside Hank Steinberg and Erwin Stoff. Production companies involved are 3 Arts Entertainment, Fox Entertainment, and Sony Pictures Television. Although initially scheduled for the 2023–24 season, the series was moved to the 2024–25 season due to production delays related to the 2023 Hollywood labor disputes. On February 26, 2025, Fox renewed the series for a 22-episode second season, making it the first drama on the network to receive a 22-episode season order since The Resident during the 2021–22 season. On March 9, 2026, Fox renewed the series for a third season consisting of 22 episodes.
Casting
On December 19, 2023, Molly Parker was cast as Dr. Amy Elias in the lead role. On March 4, 2024, Omar Metwally, Amirah Vann, Jon-Michael Ecker and Anya Banerjee were announced as series regulars, and Scott Wolf and Patrick Walker were set to recur in the series. On May 28, 2025, Walker and Charlotte Fountain-Jardim were promoted to series regulars for the second season. On June 10, 2025, Felicity Huffman joined the cast as a new series regular for the second season. On August 13, 2025, Emma Pfitzer Price was cast in a recurring capacity for the second season. On March 10, 2026, Blair Underwood was cast as a series regular for the third season. On August 25, 2026, Barrett Carnahan, Raffa Virago, Cecilia Lee and Kolton Stewart were cast in recurring capacities for the third season.
Filming
Production started in March 2024 in both Toronto, and Oakville, Ontario Canada. Filming for the second season began on June 6, 2025 and concluded on April 3, 2026. Filming for the third season started on June 29, 2026 and is scheduled to conclude April 2, 2027.
Broadcast
Doc premiered on Fox on January 7, 2025, and streaming on Hulu the next day. In Canada, the series airs on Global and is available to stream on StackTV.
The second season premiered on September 14, 2025. The third season is scheduled to premiere on September 22, 2026.
Reception
Critical response
The review aggregator website Rotten Tomatoes reported a 44% approval rating with an average rating of 4.1/10, based on 9 critic reviews. Metacritic, which uses a weighted average, assigned a score of 58 out of 100 based on 5 critics, indicating "mixed or average" reviews.