Duke of Santángelo (Spanish: Duque de Santángelo) is a hereditary title in the Peerage of Spain, accompanied by the dignity of Grandee and granted in 1497 by the Catholic Monarchs to "El Gran Capitán" (Gonzalo Fernández de Córdoba), a general who negotiated the Surrender of Granada and led the Spanish to victory in the Italian Wars. It is a victory title, making reference to the town of Città Sant'Angelo in the Province of Pescara, Italy.
The title became extinct after the death of the 3rd Duke in 1578 and was rehabilitated in 1918 by Alfonso XIII on behalf of María de la Soledad Osorio de Moscoso, the most legitimate descendant of the last Duke and a great-grandchild of Infanta Luisa Teresa of Spain.
The current Duke, Luis María de Casanova-Cárdenas, is married to Archduchess Monika of Austria (his fifth cousin once-removed), the second child of Otto von Habsburg, crown prince of Austria, and Princess Regina of Saxe-Meiningen. They have 4 children.
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Dukes of Santángelo
1497
Gonzalo Fernández de Córdoba y Enríquez de Aguilar, 1st Duke of Santángelo
Elvira Fernández de Córdoba y Manrique, 2nd Duchess of Santángelo
Gonzalo Fernández de Córdoba y Fernández de Córdoba, 3rd Duke of Santángelo
1918
María de la Soledad Osorio de Moscoso y Reynoso, 4th Duchess of Santángelo
Luis María de Casanova-Cárdenas y Barón, 5th Duke of Santángelo