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Fiona Murray

researcher

Fiona Murray

researcher (ORCID 0000-0002-5572-4810)

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About Fiona Murray

Dame Fiona Elizabeth Murray is the William Porter Professor of Entrepreneurship and Associate Dean for Innovation at the MIT Sloan School of Management. Her research focuses on the commercialisation of scientific innovation, including the role of intellectual property in knowledge diffusion and gender disparities in research funding. She is Chair of the Board of Directors of the NATO Innovation Fund.

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Facts from Wikidata (CC0). Image by U.S. Naval War College via Wikimedia Commons (CC BY 2.0).

Occupation: researcher, academic
Citizenship: United States

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Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia G-protein-coupled receptor-signaling components in membrane raft and caveolae microdomains.Increased smooth muscle cell expression of caveolin-1 and caveolae contribute to the pathophysiology of idiopathic pulmonary arterial hypertension.Increased expression of the cGMP-inhibited cAMP-specific (PDE3) and cGMP binding cGMP-specific (PDE5) phosphodiesterases in models of pulmonary hypertension Natriuretic effect by exendin-4, but not the DPP-4 inhibitor alogliptin, is mediated via the GLP-1 receptor and preserved in obese type 2 diabetic mice Adenylate cyclase 6 determines cAMP formation and aquaporin-2 phosphorylation and trafficking in inner medulla Cardiac-specific overexpression of caveolin-3 attenuates cardiac hypertrophy and increases natriuretic peptide expression and signaling Pulmonary artery smooth muscle cells from normal subjects and IPAH patients show divergent cAMP-mediated effects on TRPC expression and capacitative Ca2+ entry.University of Aberdeen University of California, San Diego

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