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Frederic M. Richards

chemist

Frederic M. Richards

Biochemist, biophysicist, crystallographer, and sailor; founder and chair of Department of Molecular Biophysics and Biochemistry at Yale University (1925-2009)

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About Frederic M. Richards

Frederic Middlebrook Richards, commonly referred to as Fred Richards, was an American biochemist and biophysicist known for solving the pioneering crystal structure of the ribonuclease S enzyme in 1967 and for defining the concept of solvent-accessible surface. He contributed many key experimental and theoretical results and developed new methods, garnering over 20,000 journal citations in several quite distinct research areas. In addition to the protein crystallography and biochemistry of ribonuclease S, these included solvent accessibility and internal packing of proteins, the first side-chain rotamer library, high-pressure crystallography, new types of chemical tags such as biotin/avidin, the nuclear magnetic resonance (NMR) chemical shift index, and structural and biophysical characterization of the effects of mutations.

Facts from Wikidata (CC0). Image by Sarah Richards via Wikimedia Commons (CC0).

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Occupation: chemist, biologist, biochemist, biophysicist
Citizenship: United States
Born: August 19, 1925
Died: January 11, 2009

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Yale University Harvard University Harvard Medical School Massachusetts Institute of Technology Phillips Exeter Academy National Academy of Sciences American Academy of Arts and Sciences American Philosophical Society Christian B. Anfinsen United States

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