Giacomo Orsini, also spelled Jacopo Orsini, was a Roman prelate, the cardinal deacon of San Giorgio in Velabro from 1371 until his death shortly after the start of the Western Schism.
- Occupation
- Catholic priest, Catholic bishop
- Position held
- protonotary apostolic, cardinal
- Born
- 1340
- Died
- August 13, 1379