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Helen Heslop

biologist

Helen Heslop

New Zealand physician-scientist

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About Helen Heslop

Helen Elisabeth Heslop is a physician-scientist from New Zealand whose clinical interests are in hematopoietic stem cell transplants. Heslop’s research focuses on immunotherapy to treat viral infections, post transplant and hematologic malignancies. She is a professor in the Department of Medicine and Pediatrics at Baylor College of Medicine and the director of the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children’s Hospital and Houston Methodist Hospital. She is also the Dan L. Duncan Chair and the associate director of clinical research at the Dan L. Duncan Cancer Center.

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Occupation: biologist, hematologist, university teacher

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Inducible apoptosis as a safety switch for adoptive cell therapy Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma Use of gene-modified virus-specific T lymphocytes to control Epstein-Barr-virus-related lymphoproliferation CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients Long-term restoration of immunity against Epstein-Barr virus infection by adoptive transfer of gene-modified virus-specific T lymphocytes Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals Baylor College of Medicine Royal Free Hospital

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