Huguette is a feminine French given name. Notable people with the name include:
Huguette Bello (born 1950), politician from Reunion
Huguette Béolet (1919–unknown), French table tennis player
Huguette Bohoussou, Ivorian footballer
Huguette Bouchardeau (1935–2026), French politician, publisher, and writer
Huguette Caland (1931–2019), Lebanese painter, sculptor and fashion designer
Huguette M. Clark (1906–2011), French-American heiress and recluse
Huguette Delavault (1924–2003), French mathematician
Huguette Desjardins (born 1938), Canadian artist
Huguette Dreyfus (1928–2016), French harpsichordist
Huguette Duflos (1887–1982), French actress
Huguette Gaulin (1944–1972), French novelist
Huguette Labelle (born 1939), retired Canadian civil servant
Huguette Lachapelle (1942–2021), Canadian politician
Huguette Oligny (1922–2013), Canadian actress
Huguette Peeters (born 1936), Belgian swimmer
Huguette Plamondon (1926–2010), Canadian politician and trade unionist
Huguette Tiegna (born 1982), French politician
Huguette Tourangeau (1940–2018), French-Canadian operatic mezzo-soprano