Irene Syrikaina was the third Empress-consort of Manuel I of Trebizond. She may be the same Irene Syrikaina whom Michael Panaretos mentions was stoned to death in September 1332 in the purges that followed Basil Megas Komnenos's accession to the throne.
- Citizenship
- Byzantine Empire
- Born
- 1201
- Died
- March 1263
