Television
Friedlander played the role of a techie on the Al Franken sitcom LateLine in 1999. Over the 2000s Friedlander held guest roles on several television shows, including Spin City, Curb Your Enthusiasm and Flight of the Conchords, as well as providing voices for characters on the animated series Wonder Showzen and Xavier: Renegade Angel. Friedlander made regular appearances on the entertainment and pop-culture program Best Week Ever. He appeared as the online co-host of the 2009 TV Land Awards, alongside main stage host Neil Patrick Harris.
Friedlander was a regular cast member of the sitcom 30 Rock throughout its entire run, from October 11, 2006, to January 31, 2013. His character, Frank Rossitano, is a sarcastic and wisecracking writer on the fictional show TGS with Tracy Jordan Frank is lazy, slovenly, and lives with his mother (played by Patti Lupone). He is also sex-obsessed, which he often reveals by way of vulgar and sexually suggestive comments. Friedlander has stated that Frank Rossitano is based on at least two writers with whom Tina Fey used to work at Saturday Night Live. His ever-changing, slogan-bearing trucker hats also became a running gag on the show. Friedlander makes his hats himself and created enough of them to be able to wear a different one in each scene of 30 Rock, which is about three hats per show.
Friedlander has appeared on late-night talk shows such as Late Night with Conan O'Brien, The Daily Show with Jon Stewart, The Daily Show with Trevor Noah, The Tonight Show with Jay Leno, Late Night with Jimmy Fallon and Last Call with Carson Daly. In 2010 Friedlander appeared in 2 episodes of the children's series Sesame Street. He also appeared as a panelist on The Burn with Jeff Ross in 2013.
In May and June 2014, Friedlander narrated ESPN's Inside: U.S. Soccer's March to Brazil six-part series in preparation for the World Cup in Brazil.
He has appeared on MSNBC's Last Word with Lawrence O'Donnell and provided personal commentary on The World Cup and soccer in general.