2018–present: Breakthrough and mainstream success
In 2018, Luo starred in the historical romance drama Princess Silver as a kind prince who inherits a deadly poison from his mother before birth. That same year, he rose to prominence starring as the kind Night Immortal who seeks to avenge his mother's death in fantasy romance drama Ashes of Love. The drama topped television ratings and online web rankings and Luo's portrayal of a morally ambiguous antagonist was met with critical acclaim.
The following year, Luo was cast in the romance drama Broker as a morally ambiguous corporate spy. In 2020, Luo starred in the wuxia romance drama And The Winner Is Love as the graceful young master of the Yueshang Valley. That same year, Luo was cast in the xianxia drama Immortality as a selfless and fearless grandmaster.
He also starred in the workplace romance drama Love is Sweet. The drama was iQiyi's most popular romance drama in 2020, and Luo received positive reviews for his role as an arrogant and charming investment bank executive. NetEase Entertainment's review praised Luo's acting, stating that, "Luo Yunxi's portrayal of Yuan Shuai is natural and expressive, resonating with the audience and evoking memories of their own unrequited love experiences."
Luo continued his foray into modern dramas where he was cast as a secretive CEO in Lie to Love, a lawyer-turned-volunteer rescue worker in Light Chaser Rescue and as a genius neurosurgeon who spearheads research on Huntington's disease in the 2023 medical romance drama Love is Panacea.
In 2023, Luo received international acclaim for his starring role in xianxia drama Till the End of the Moon as a prince who is born with an evil bone and must rebel against his destiny of becoming the Devil God.The drama premiered on Youku on April 6, 2023 and was a wild commercial success, both in China and in the international market. Youku had the highest number of downloads on the App Store since 2018. The drama's first-day market share was 22.76%, making it the most-watched period drama since 2020, and Luo's portrayal of the anti-hero received positive reviews. The show was broadcast in South Korea, Hong Kong, Thailand, Taiwan, and Malaysia.
Following the success of Till the End of the Moon, Luo starred in fantasy wuxia drama Whispers of Fate as a highly skilled martial artist who travels across the jianghu in his fight against destiny. The drama premiered on Mango TV and Migu Video on October 24, 2025 followed by an international release across more than 110 countries. According to the 2025 domestic TV drama viewership report released by the National Radio and Television Administration, Whispers of Fate achieved a local audience rating of 1.601% during its broadcast on Hunan TV and ranked first in viewership among TV dramas on Mango TV in 2025.
Later that year, Luo starred in 2025 suspense thriller The Truth Within as a forensic doctor. In addition, Luo portrayed a constable with a hidden identity in the supernatural period drama Shadow Punisher.
