Manuel Pérez de Guzmán y Pimentel, 12th Duke of Medina Sidonia (1671–1721) became Duke of Medina Sidonia in 1713.
Biography
He was the only son of Juan Claros Pérez de Guzmán, 11th Duke of Medina Sidonia and Antonia Teresa Pimentel.
He was married in 1687, aged 16, to the 17-year-old Luisa Maria de Silva Mendoza. She was a daughter of Gregorio Maria Domingo, the 5th Duke of Pastrana, 5th Duke of Estremera and 9th Duke of el Infantado. They had 10 children, including :
Domingo (1691-1739), XIII Duke of Medina Sidonia.
Francisca Bibiana, married in 1721 José María Téllez-Girón, 7th Duke of Osuna.
Juana, married in 1713, Fadrique Vicente de Toledo Osorio, 9th Marquis of Villafranca del Bierzo.
Rosa, married the 6th Marquis of Ariza and Admiral of Aragón.