Mario Rodríguez may refer to:
Contents
Sports
Association football
Mario Rodríguez (footballer, born 1937) (1937–2015), Argentine footballer
Mario Rodríguez (footballer, born 1960), Chilean footballer
Mario Rodríguez (footballer, born 1972), Peruvian footballer
Mario César Rodríguez (born 1975), Honduran footballer
Mario-Ernesto Rodríguez (born 1976), Uruguayan-Italian footballer
Mario Rodríguez (footballer, born 1978), Mexican footballer
Mario Rodríguez (footballer, born 1981), Guatemalan footballer
Mario Rodríguez (footballer, born 1991), Mexican footballer
Mario Rodríguez (soccer, born 1994), American soccer player for Dynamo Dresden
Mario Rodríguez (footballer, born 1995), Mexican footballer
Mario Rodríguez (footballer, born 1997), Spanish footballer
Other sports
Mario Rodríguez (baseball) (1909–?), Cuban baseball player
Mario Rodríguez (weightlifter), Dominican Republic Olympic weightlifter
Mario Rodriguez (fencer) (born 1959), American Paralympic fencer
Mario Rodríguez (boxer) (born 1988), Mexican professional boxer
Others
Mario Rodríguez Cobos (1938–2010), Spanish-Argentine writer and spiritual leader