Early life and education
Martha Wayles was born on October 30, 1748 (O.S. October 19, 1748), the only surviving child born to Martha Eppes Wayles (1721–1748) and John Wayles (1715–1773), near Colonial Williamsburg in Charles City County, Virginia.
Martha's mother, Martha Eppes Wayles, had previously given birth to twins in 1746, but neither survived; the girl was stillborn and the boy died hours after his birth. Martha was nicknamed "Patsy". Martha's father John was a Lancaster-born emigrant to the Thirteen Colonies who worked as an attorney and prosperous planter and slave trader. In addition, he was an agent for the Farrell and Jones company based in Bristol, undertaking activities such as debt collection on their behalf. Martha Eppes Wayles was a daughter of Francis Eppes, a settler of the Bermuda Hundred, an early Virginian colony established along the Appomattox River. While little is known of Martha Eppes Wayles' life, she had an appreciation for fine literature, such as her favorite novel, Tristram Shandy and Les Aventures de Télémaque. (Her rebound version of the book, The Adventures of Telemachus, contains her signature on the title page and resides at the Library of Congress).
Martha Wayles had two stepmothers, neither of whom lived long after their marriages to John Wayles, and through one stepmother she had four half-sisters. Wayles married Tabitha Cocke, of Malvern Hill. They had four children: Sarah, Elizabeth, Tabitha and Anne. Sarah died in infancy. Tabitha and Anne married the Skipwith brothers, Robert and Henry, respectively. Tabitha Skipwith died with her first childbirth. Nancy Skipwith, "Aunty Skipwith" to the Jefferson children and grandchildren, died in 1798. Elizabeth married Francis Eppes, Martha's cousin, and had two sons, Richard and John Wayles Eppes, the latter of whom married Thomas Jefferson's second daughter, Mary Jefferson. Wayles' second wife died most likely after the birth of Anne in August 1756 and before he married his third wife in January 1760.
On January 26, 1760, Wayles married his third wife, Elizabeth Lomax Skelton (she was the widow of Reuben Skelton, an older brother of Bathurst Skelton, his daughter Martha's first husband). Without producing a child with Wayles, she died on February 10, 1761. John Wayles then took Betty Hemings as a concubine, and gave Martha additional half-siblings. Martha likely received her education—including literature, dance, music, French language and Bible study— from private tutors or women in the family. She became the "Lady of the House" after her second stepmother died when she was 13 years of age and was often a hostess to John Wayles' social events and helped manage his business and household affairs. She knew how to make candles, soap, butter and remedies for illnesses.