Perth Wildcats (2010–2017)
On 7 April 2010, Knight signed a three-year deal with the Perth Wildcats, returning to the NBL after one season in Hungary. He was lured to the club by his Sydney Spirit comrades, Damian Martin and Rob Beveridge, with the pair coming off an NBL championship with the Wildcats in 2009–10.
Upon moving to Perth, Knight joined the Rockingham Flames of the State Basketball League (SBL) and had a three-game stint with the club in mid-July.
Knight's debut season for the Wildcats began positively before a left calf injury suffered on 12 December 2010 against the Melbourne Tigers ruled him out for two months. Further injuries to Jesse Wagstaff and Shawn Redhage threw the Wildcats' season into disarray as they stumbled through the regular season with inadequate injury replacements. Knight returned to action on 11 February 2011 and helped the team reach the playoffs with a fourth-place finish and a 16–12 record. In their semi-final series against the first-seeded New Zealand Breakers, the Wildcats took Game 1 in Auckland, but then lost Games 2 and 3 to bow out of the playoffs with a 2–1 defeat. In 18 games for the Wildcats in 2010–11, Knight averaged 12.4 points, 6.7 rebounds and 1.2 assists per game.
Following the 2010–11 NBL season, Knight returned to the SBL and joined the Willetton Tigers. He was a dominant force for the Tigers over his first seven games, but in his eighth appearance for the club on 17 June, he suffered a slight calf strain to the same calf he tore on 12 December 2010. The strain ruled him out for a month of action, as he returned to the line-up on 16 July for a four-minute stint. In nine games for the Tigers in 2011, Knight averaged 18.9 points, 7.7 rebounds, 1.4 assists and 1.1 steals per game.
Knight was relatively injury free in 2011–12 and was able to lead the Wildcats to a second-place finish with a 19–9 record. After defeating the Gold Coast Blaze 2–1 in the semi-finals, the Wildcats moved on to the Grand Final series where they faced the New Zealand Breakers. They lost Game 1 in Auckland but were able to tie the series at 1–1 with a Game 2 victory in Perth, leaving the series to a Game 3 decider in Auckland. In a tightly fought game, the Wildcats went down to the Breakers 79–73, finishing runners-up with a 2–1 defeat. In 29 games for the Wildcats in 2011–12, Knight averaged 10.8 points, 5.4 rebounds and 1.3 assists per game.
After undergoing off-season shoulder surgery, Knight entered the 2012–13 season with the mindset of wanting to be the dominant big guy in the NBL and was set to be the team's go-to guy in the paint. Knight embraced the responsibility that came with being the team's primary focus under the basket, and excelled in the Wildcats' season-opening win over the New Zealand Breakers, earning the NBL's Player of the Week award for a 20-point, nine-rebound effort. He went on to lead the Wildcats to a 22–6 record, good for second behind their arch rivals the Breakers, who amassed just three losses on the season. After sweeping the Wollongong Hawks in the semi-finals, the Wildcats returned to the Grand Final series where they again faced the Breakers – their third time facing the Breakers in a playoff series in as many years. However, with the team missing Damian Martin through injury, the Wildcats stumbled to a 2–0 defeat, as the Breakers claimed their third championship in a row, winning Game 2 in Perth at Perth Arena. Despite another disappointing end to a good overall season, Knight picked up numerous accolades for the 2012–13 season, including finishing runner-up for the Wildcats MVP, being named in the All-NBL first team and voted as the starting centre in the All-Star game, reaffirming his status as the league's premier big man. In 27 games for the Wildcats in 2012–13, he averaged 13.7 points and 7.2 rebounds per game.
On 5 May 2013, Knight re-signed with the Wildcats on a three-year deal. He missed much of the 2013–14 NBL season through injury. The Wildcats returned to the Grand Final in 2014 and defeated the Adelaide 36ers 2–1 to win the NBL championship as Knight claimed his first title. In 18 games for the Wildcats in 2013–14, he averaged 10.1 points, 5.5 rebounds and 1.3 assists per game.
On 16 November 2014, Knight played his 100th game for the Wildcats in an 85–66 win over the Sydney Kings. In 30 minutes of action, he recorded 16 points and eight rebounds. On 9 January 2015, he was ruled out for six weeks with a toe injury. After missing six games, he returned to action earlier than expected, suiting up on 1 February against Sydney. The 2014–15 season turned out to be a near carbon copy of the 2010–11 season for the Wildcats as they finished fourth on the ladder with a 16–12 record and were knocked out in the semi-finals by the Cairns Taipans, failing to defend their 2013–14 title in a season that was plagued with injuries. In 24 games for the Wildcats in 2014–15, Knight averaged 10.5 points, 7.0 rebounds and 1.7 assists per game. He subsequently earned All-NBL second team honours.
For the first time in his Wildcats career, Knight had an injury-free season in 2015–16. With the team's acquisition of Nathan Jawai, Knight was able to move to his natural position of power forward. The Wildcats returned to the grand final and beat the New Zealand Breakers 2–1 to win the championship. Knight appeared in 33 of the team's 34 games in 2015–16, averaging 11.6 points, 7.9 rebounds and 1.4 assists per game. He earned All-NBL second team honours for the second straight year.
On 19 April 2016, Knight re-signed with the Wildcats on a two-year deal, a month after undergoing shoulder stabilisation surgery on his left arm. Unfortunately, injury struck down Knight again during the 2016 off-season. On 12 September 2016, he was ruled out for two months after suffering a subluxation of his right shoulder during training a week earlier. However, the joint responded well to rehab and after a week of full training with the team, Wildcats medical staff gave him the all-clear on 20 October 2016. He made his season debut the following day, recording 12 points and eight rebounds in an 80–73 win over the Illawarra Hawks. On 13 November, he had a season-best game with 24 points and 13 rebounds in an 87–86 overtime loss to the New Zealand Breakers. After averaging 13 points per game over his first eight games, Knight's form began to decline in December as he scored in double figures just three times over the next 14 games. He also had only one double-digit rebounding game during that stretch. In the Wildcats' regular season finale on 12 February 2017, Knight had his best game since late November with a double-double of 15 points and 10 rebounds to help lead the Wildcats to a 96–94 win over Melbourne United in Melbourne. The win propelled the Wildcats into their 31st consecutive NBL Finals appearance, as they finished the regular season in third place with a 15–13 record. Knight helped the Wildcats win through to another NBL Grand Final after sweeping the second-seeded Cairns Taipans in the semi-finals. In Game 1 of the best-of-five grand final series, Knight scored 18 points to help lift the Wildcats to an 89–77 win over the Illawarra Hawks. In Game 2 of the series, Knight had to be helped off the court after seemingly innocuous contact from teammate Casey Prather early in the third quarter. He was subsequently ruled out of Game 3. Despite being without Knight, the Wildcats successfully defended their title with a 3–0 series sweep. It marked the Wildcats' eighth championship and Knight's third. Knight appeared in 27 of the team's 33 games, averaging 9.4 points, 6.0 rebounds and 1.6 assists per game.
Knight sustained two head knocks over the last month of the 2016–17 NBL season, both of which resulted in him being unable to complete the game and missing a subsequent contest. Wildcats managing director Nick Marvin acknowledged that the club would consult with Knight during the 2017 off-season, with six concussion-related incidents in six years raising concerns over his long-term health.
On 1 July 2017, Knight revealed that the 2017–18 NBL season would be his last. After battling shoulder problems and concussion in 2016–17, Knight had hoped to avoid more injuries in his final season. However, on 13 September 2017, he was ruled out for the remainder of the club's pre-season games with a thumb injury. The injury occurred in the Wildcats' opening game of the NBL Blitz. Scans revealed a small fracture and ligament damage in his right thumb, with Wildcats medical staff opting to take a non-surgical approach to repairing the injury. The injury-prone Knight suffered head knocks against Brisbane and Cairns early in the season, but concerns for his future were only fully taken into account following another head knock that came accidentally at training on 30 October. As a result, Knight brought forward his retirement plans, calling time on his 236-game NBL career on 6 November 2017. He finished his career with 2,800 points and 1,646 rebounds.
