His sons
When Mehmed died his sons – Saadet, Safa and Murad – fled to the steppe. They were accompanied by some of the Mansur clan who lived in the northwestern, steppe-like part of Crimea.
Saadet: Three months later, Saadet and his brothers led 15000 Nogais south, seeking to avenge their father. They took the capital and Saadet declared himself khan as Saadet II Giray. Islyam fled to the Turks at Kaffa where he was besieged. After three months 4000 Turks arrived with artillery and drove Saadet back to the steppe. In the spring of 1585 Saadet tried again but was defeated before he reached Crimea. For more see İslâm II Giray.
The three brothers were now in danger since any bold chieftain might seize them and sell them to Islyam. Saadet fled east to Chopan, the Shamkhal of the Kumyks on the Caspian Sea. Chopan probably wanted a bargaining chip to protect his independence, since in the last reign Turkish and Crimean troops had several times marched through his lands to attack the Persians. The Shah of Persia was happy with Saadet's arrival and sent him a decorated saber which he suggested be used against the Turks. See Ottoman–Safavid War (1578–90).
The Russians invited him from Kumykia to Astrakhan, perhaps to join his brother Murad. It was learned in Crimea that a certain Khoja-bey had left Istanbul, bypassed Crimea and landed at Azov with messages for Saadet and Murad. We do not know what was said, but in the autumn of 1587 Saadet was found dead at Astrakhan. It is thought that the Russians had him murdered, fearing that he might go over to the Turks. The whole business remains mysterious.
Safa: During Saadet's revolt Safa was his kalga. After Saadet's second defeat, Safa went to Circassia. In the autumn of 1586 he joined Saadet in Kumykia. In October 1586 the Russians invited Safa and Saadet to join their brother Murad at Astrakhan. Saadet went, but Safa refused. In 1587 he was in Circassia or with the Little Nogai Horde to the north. In the spring of 1588 Khan Islyam died and was replaced by Gazi II. In May 1588 Safa returned to Crimea and became Gazi's Nureddin. In June he met the Russian ambassador concerning Murad. In 1591 he participated in Gazi's attack on Russia. Returning from the campaign he fell ill and died in Crimea.
Murad chose a stronger protector and went to the Russians at Astrakhan. The Russians hoped to use him as a puppet khan just as they had done at Kazan. Murad went to Moscow in the spring of 1586, was shown great honor and returned to Astrakhan in September. He affected royal airs and called himself "Lord of the Four Rivers" (Don, Volga, Ural and Terek), but was closely watched by the Russians. He was told to unite the Nogais, Kabardians and Kumyks against Crimea and Turkey. Urus Bey of the Nogais submitted very reluctantly and sent a complaint to the sultan. In the spring of 1587 Islyam heard that the czar had sent Murad 30000 streltsi and Cossacks in preparation for an attack on Crimea at the end of the year. In response, Alp and Selyamet made a raid on the Oka. The Russians claimed success, but the raid reduced their support for Murad. The Russians pretended that they had sent the men to fight the Poles, not the Crimeans.
Unhappy with Murad's demands, Urus-Bey sent an ambassador to the sultan offering to become a Turkish subject and receive a Turkish governor, asking for Adil Giray's fort of Bola-Serai to replace Saraichik which the Volga Cossacks had destroyed and proposed a new Turkish campaign to liberate Astrakhan. Some time before the Sultan had received a proposal from Bukhara for a joint attack on Astrakhan to open up communications north of the Caspian. Both were at war with Persia. The vizier Piyale-Pasha visited both Bukhara and the Nogais and reported that the capture of Astrakhan was feasible. The sultan ordered Urus and Islyam to prepare for a Volga campaign in the spring of 1588. Islyam would be in charge. Piyale-Pasha began filling Kaffa with food and equipment. (When Islyam died in 1588 the campaign was cancelled, the Turkish troops were sent to the Persian front and the galleys returned to the Mediterranean.)
In the winter if 1586/87 Murad went to the Kumyks to marry the Shamkhal's daughter and bring him into the Russian orbit, while Saadet moved from Kumykia to Astrakhan. In early 1587 he returned to Astrakhan without a wife. That autumn Saadet died and Murad married his widow. In 1588 Khan Islyam died and was replaced by Gazi II. In late 1588 Gazi sent ambassadors to Moscow asking that Murad be released. The Russians said that he was free to go. He went to Moscow in February 1589 and again in the summer of 1590. In 1591 Murad decided to return to Crimea without the Czar's permission. The Russians made no attempt to stop him, but on the eve of his departure he was found dead along with Kumyk, son of his brother Saadet. The Russians blamed his death on Tatar “sorcerers" and had them burnt at the stake. His wife, Es-Tourgan, whose previous husband Saadet had died under similar circumstances, wrote to Crimea saying that her husband and stepson had been poisoned. Later, as part of a peace deal on the eve of the Hungarian war, Es-Tourgan was allowed to go to Crimea along with Saadet's sons Devlet, Mehmed and Sahin.