2001–present
With his next film, Ali (2001), starring Will Smith, Mann started experimenting with digital cameras. For his action thriller film Collateral, which was released in 2004, Mann cast Tom Cruise against type by giving him the role of a hitman. Mann shot all of the exterior scenes digitally so that he could achieve more depth and detail during the night scenes while shooting most of the interiors on film stock. Jamie Foxx was nominated for an Academy Award for his performance in Collateral. Also in 2004, he produced Martin Scorsese's The Aviator, based on the life of Howard Hughes, which he had developed with Leonardo DiCaprio. The Aviator was nominated for an Academy Award for Best Picture but lost to Million Dollar Baby. After Collateral, Mann directed the film adaptation of Miami Vice which he also executive produced. The film starred Colin Farrell as Don Johnson's character James "Sonny" Crockett, and Foxx filling Philip Michael Thomas' shoes as Ricardo Tubbs.
Mann directed the 2002 "Lucky Star" advertisement for Mercedes-Benz, which took the form of a film trailer for a purported thriller featuring Benicio del Toro. In the fall of 2007, Mann directed two commercials for Nike. The ad campaign "Leave Nothing" features football action scenes with former NFL players Shawne Merriman and Steven Jackson, as well as using the score "Promontory" from the soundtrack of The Last of the Mohicans. Mann directed the 2008 promotional video for Ferrari's California sports car.
Mann was producer with Peter Berg as director for The Kingdom and Hancock. Hancock stars Smith as a hard-drinking superhero who has fallen out of favor with the public and who begins to have a relationship with the wife (Charlize Theron) of a public relations expert (Jason Bateman), who is helping him to repair his image. Mann makes a cameo appearance in the film as an executive. In 2009, Mann wrote and directed Public Enemies for Universal Pictures, about the Depression-era crime wave, based on Bryan Burrough's nonfiction book, Public Enemies: America's Greatest Crime Wave and the Birth of the FBI, 1933–34. It starred Johnny Depp and Christian Bale. Depp played John Dillinger in the film, and Bale played Melvin Purvis, the FBI agent in charge of capturing Dillinger.
In 2009, Mann signed a petition calling for the release of film director Roman Polanski, who had been arrested in Switzerland in relation to his 1977 charge for drugging and raping a 13-year-old girl.
In January 2010, it was reported by Variety that Mann, alongside David Milch, would serve as co-executive producer of new TV series Luck starring Dustin Hoffman and Dennis Farina. The series was an hour-long HBO production, and Mann directed the series' pilot. Although initially renewed for a second season after the airing of the pilot, it was eventually cancelled due to the death of three horses during production.
In February 2013, it was announced that Mann had been developing an untitled thriller film with screenwriter Morgan Davis Foehl for over a year, for Legendary Pictures. In May 2013, Mann started filming the action thriller, named Blackhat, in Los Angeles, Kuala Lumpur, Hong Kong and Jakarta. The film, starring Chris Hemsworth as a hacker who gets released from prison to pursue a cyberterrorist across the globe, was released in January 2015 by Universal. It received mixed reviews and was a commercial disaster, although several critics included it in their year-end "best-of" lists.
Mann directed the first episode of the 2022 crime series Tokyo Vice for HBO Max, his first directing work since Blackhat. In August the same year, Mann released Heat 2, a novel he had co-written with Meg Gardiner. The book takes place from 1988 to 2000, covering events that happen before and after the 1995 film. The same month, Mann began shooting Ferrari starring Adam Driver and Penélope Cruz in Modena. The film premiered at the 80th Venice International Film Festival and was released in the US in December 2023. Ferrari received generally positive reviews from critics and attained moderate box office success in the United States, while under-performing in overseas box office.
Mann intends for his next film to be Heat 2, which will be distributed by Amazon MGM Studios under the United Artists division. Bruckheimer and Mann will both produce, marking the first time they have worked together since Thief. Leonardo DiCaprio and Christian Bale are reportedly cast in the lead, with Stephen Graham, Jason Clarke, Inde Navarrette and Adam Driver in talks for roles. Production is planning to start in November 2026.