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Peter Leadlay — latest news, discussion & facts — IJR

Peter Leadlay

biochemist

Peter Leadlay

biochemist

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About Peter Leadlay

biochemist

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Occupation: biochemist, professor
Born: 1950
Website: http://www.csap.cam.ac.uk/network/peter-leadlay/

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Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans Combinatorial biosynthesis of reduced polyketides Divergent sequence motifs correlated with the substrate specificity of (methyl)malonyl-CoA:acyl carrier protein transacylase domains in modular polyketide synthases Role of type II thioesterases: evidence for removal of short acyl chains produced by aberrant decarboxylation of chain extender units Engineering broader specificity into an antibiotic-producing polyketide synthase The structure of docking domains in modular polyketide synthases Cloning and sequence analysis of genes involved in erythromycin biosynthesis in Saccharopolyspora erythraea: sequence similarities between EryG and a family of S-adenosylmethionine-dependent methyltransferases