Overview
Robert Royston Amos Coombs FRS FRCPath FRCP (9 January 1921 – 25 January 2006) was a British immunologist, co-discoverer of the Coombs test (1945) used for detecting antibodies in various clinical scenarios, such as Rh disease and blood transfusion.
Biography
He was born in London but attended Diocesan College in Cape Town. Subsequently he returned to Britain and studied veterinary medicine at the University of Edinburgh. In 1943 he entered King's College, Cambridge, where he commenced work on a doctorate, which he gained in 1947. Before finishing his doctorate, he developed and published methods to detect antibodies with Arthur Mourant and Robert Russell Race in 1945. This is the test now referred to as the Coombs test, which, according to the legend, was first devised while Coombs was travelling on the train.
Coombs became a professor and researcher at the Department of Pathology of University of Cambridge, becoming a Fellow of Corpus Christi College, and a founder of its Division of Immunology. He was appointed the fourth Quick Professor of Biology in 1966 and continued to work at Cambridge University until 1988. He is reported to have said that "[r]ed blood cells were primarily designed by God as tools for the immunologist and only secondarily as carriers of haemoglobin".
In November 1956, Coombs founded the British Society for Immunology alongside John H. Humphrey, Bob White, and Avrion Mitchison. He was an honorary member of the British Society for Immunology.
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