Sayama (written: 佐山) is a Japanese surname. Notable people with the surname include:
Ayaka Sayama (佐山 彩香; born 1993), Japanese gravure idol
Jackson Sayama (ジャクソン・サヤマ; born 1996/1997), American politician
Kiyoko Sayama (佐山 聖子), Japanese animator and director
Masahiro Sayama (佐山 雅弘; 1953–2018), Japanese pianist
Momoko Sayama (左山 桃子; born 1992), Japanese footballer
Satoru Sayama (佐山 聡; born 1957), Japanese writer, professional wrestler, mixed martial artist