ER is an American medical drama television series created by Michael Crichton that aired on NBC from September 19, 1994, to April 2, 2009. It was produced by Constant c Productions and Amblin Television, in association with Warner Bros. Television. The series follows the inner life of the emergency room (ER) of fictional Cook County General Hospital in Chicago, and various critical issues faced by the room's physicians and staff.
ER featured a large ensemble cast that changed dramatically over its long run. The main cast was augmented by a wealth of recurring characters and award-winning guest stars.
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Main cast
The original starring cast consisted of Anthony Edwards as Dr. Mark Greene, George Clooney as Dr. Douglas "Doug" Ross, Sherry Stringfield as Dr. Susan Lewis, Noah Wyle as medical student (later Dr.) John Carter, and Eriq La Salle as Dr. Peter Benton. Julianna Margulies guest starred in the pilot as Nurse Carol Hathaway before becoming part of the regular cast.
The first additions to the main cast came in Season 2 with Gloria Reuben signing on as Physician Assistant Jeanie Boulet (recurring character in Season 1), and in Season 3 with Laura Innes as Dr. Kerry Weaver (recurring character in Season 2). In Season 4, Maria Bello signed on as Dr. Anna Del Amico (recurring character at the end of Season 3) and Alex Kingston joined the cast as Dr. Elizabeth Corday. Season 5 saw the addition of Kellie Martin as medical student Lucy Knight.
George Clooney's departure towards the end of Season 5 started a major cycle of main cast changes over the next few years. Season 6 opened with the addition of Paul McCrane as Dr. Robert "Rocket" Romano (recurring character in both Seasons 4 and 5), Croatian actor Goran Višnjić as Dr. Luka Kovač, and Michael Michele as Dr. Cleo Finch. A bit later in the season Erik Palladino joined as Dr. Dave Malucci, and Ming-Na returned to the series as Dr. Jing-Mei "Deb" Chen, reprising a recurring character she portrayed in Season 1. Soon after, Maura Tierney was added as Nurse (later Dr.) Abigail "Abby" Lockhart. Season 8 saw the arrival of Sharif Atkins as medical student (later Dr.) Michael Gallant, as well as the return of Dr. Susan Lewis when Sherry Stringfield reprised her role after having left the series in Season 3.
Mekhi Phifer joined the cast in Season 9 as Dr. Gregory "Greg" Pratt (recurring character at the end of Season 8). Season 10 saw the addition of Parminder Nagra as medical student (later Dr.) Neela Rasgotra and Linda Cardellini as Nurse Samantha "Sam" Taggart. Shane West joined the cast in Season 11 as Dr. Ray Barnett and Scott Grimes became part of the main cast in Season 12 as Dr. Archie Morris (recurring character in Seasons 10 and 11). Season 13 saw the addition of John Stamos as Dr. Anthony "Tony" Gates, reprising a role he had originated in Season 12 when he portrayed Gates the paramedic/medical student. Season 15 saw the final additions to the main cast, with David Lyons signing on as Dr. Simon Brenner (recurring character towards the end of Season 14) and Angela Bassett as Dr. Catherine "Cate" Banfield.
Notably, of the 26 main cast members that starred throughout ER's 15-season run, only seven were not featured in the final season: Gloria Reuben, Maria Bello, Kellie Martin, Michael Michele, Erik Palladino, Ming-Na, and Sharif Atkins. In addition, only four main cast members never made a return appearance of any type following their original stint: Maria Bello, Kellie Martin, Erik Palladino, and Mekhi Phifer.
Departures from the main cast
Sherry Stringfield's first departure from the show was in 1996, when her character, Susan Lewis, moved to Phoenix, Arizona, in the Season 3 episode "Union Station." In 2001, Stringfield returned to the series, reprising her role of Dr. Lewis, in the Season 8 episode "Never Say Never." She departed again after the Season 12 premiere, "Cañon City." This departure was not depicted, but was mentioned by character Kerry Weaver two episodes later, in "Man With No Name", as not coming in due to interviewing for a tenured position, having been denied tenure at County, and again later in "Wake Up," when Weaver explains that Susan accepted a tenure-track position at a hospital in Iowa City, Iowa. Stringfield returned once again for the series finale.
After playing Anna Del Amico for one season, Maria Bello was not part of the ensemble cast when Season 5 began. Like Susan Lewis's second exit, her character's departure was mentioned but not depicted: in the season premiere, "Day for Knight," John Carter explains to new medical student Lucy Knight that the locker she is inheriting previously belonged to Del Amico, who returned to Philadelphia to rejoin a prestigious Pediatrics unit there and be with her family and boyfriend.
George Clooney left the show in the Season 5 episode "The Storm (Part II)," when his character, Doug Ross, resigned before being fired for his involvement in a patient's death. Clooney made a cameo appearance in the Season 6 episode "Such Sweet Sorrow" when his character reunited with Carol Hathaway and appeared in the Season 15 episode "Old Times" where his character was the attending physician caring for a terminal organ donor in Seattle.
Gloria Reuben departed early in Season 6, in the episode "The Peace of Wild Things," when her character, Jeanie Boulet, decided to become a stay-at-home mom and care for her newly adopted HIV-positive baby. Reuben returned in the Season 14 episode "Status Quo" when her character's son was brought into the ER.
Kellie Martin, who played medical student Lucy Knight, left the series midway through Season 6 in the episode "All in The Family," when her character was killed by a patient with undiagnosed schizophrenia; his psychotic break occurred before a backed-up psychiatry department could arrive in the ER for a consult.



