St. Charles County is located in the central eastern part of the U.S. state of Missouri. As of the 2020 census, the population was 405,262, making it Missouri's third-most populous county. Its county seat is St. Charles. The county was organized October 1, 1812, and named for Saint Charles Borromeo, an Italian cardinal.

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Facts from Wikidata (CC0). Image by Tysports via Wikimedia Commons (CC BY-SA 4.0).

St. Charles County

county in Missouri, United States

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