Theophano (; died after 811) was the empress consort of Staurakios of the Byzantine Empire. According to the chronicle of Theophanes the Confessor, Theophano was a relative of Irene (reigned 797–802). Both women were from Athens but the nature of their relation to each other is not known.
On 20 December 807, Theophano married Staurakios. The date of their marriage was recorded by Theophanes. Staurakios was the only known son of Nikephoros I. He was co-emperor with his father since 803. Theophano had been betrothed to another man but took place in the imperial bride-show. She was possibly chosen to legitimise the connection of the new dynasty to their predecessor.
Her father-in-law is presumed to have been a widower by the time he was elevated to the throne. In the absence of a senior empress, Theophano was the only Empress during his reign.
On 26 July 811, Nikephoros was killed while fighting against Krum of Bulgaria at the Battle of Pliska. Much of the Byzantine army was annihilated with him and the battle is considered one of the worst defeats in Byzantine history. Among the few survivors was Staurakios who succeeded as emperor.
