Tokugawa Mitsusada (徳川 光貞; January 28, 1627 – September 25, 1705) was a daimyō in Japan during the Edo period (1603–1868). Mitsusada was born as the son and heir of Tokugawa Yorinobu and a grandson of Tokugawa Ieyasu with the childhood name Nagatomimaru (長福丸). Among his sons was the eighth Tokugawa shōgun Yoshimune. Norihime, a daughter of his, married Ichijō Kaneteru. He married the daughter of Prince Fushimi-no-Miya Sadakiyo, Yaso-no-Miya Teruko (who is also the sister of Asa no Miya Akiko who was 4th shōgun, Tokugawa Ietsuna's wife).
One of the gosanke, Mitsusada ruled the Wakayama Domain from its castle, his birthplace, in Wakayama. He reached the Junior Second court rank while alive, and was awarded the Junior First rank posthumously; he also held the ceremonial post of gon-dainagon. His grave is at Chōhō-ji in Wakayama. His other sons were Tokugawa Tsunanori (1665–1705) and Tokugawa Yoritomo (1680–1705).
Family
Father: Tokugawa Yorinobu
Mother: Nakagawa-dono (1601–1666)
Wife: Yaso-no-Miya Teruko later Tenshin'in
Concubines
Yamada-dono later Zuiyoin
Miyazaki-dono
Chigusa-dono
Oyuri no Kata (1655–1726)
Children:
Tokugawa Tsunanori (1665–1705) by Yamada, 4th Lord of Kishu and married Tsuruhime, daughter of 5th shōgun Tokugawa Tsunayoshi
Jirokichi
Tokugawa Yorimoto (1680–1705) by Miyazaki, 5th Lord of Kishu
Tokugawa Yoshimune by Oyuri
Sakae-Hime married Uesugi Tsunanori of Yonezawa Domain
Norihime married Ichijo Kaneteru
Tsunahime by Chigusa
Ikuhime married Satake Yoshimitsu