Recurring
Daniel Gillies as Mark Monroe (also starring season 1; recurring season 3; guest seasons 2, 4), Mel's late husband, who is shown in flashbacks.
Lexa Doig as Paige Lassiter (seasons 1, 4; guest seasons 2, 5), the owner of a bakery truck named "Paige's Bakeaway" and mother of Christopher
Lynda Boyd as Lilly (seasons 1–3; guest season 4), a friend of Connie and Hope
Nicola Cavendish as Connie, one of Hope's friends who runs the town's general store and a member of Virgin River's knitting circle. She also later takes over and runs Paige's Bakeaway.
Ian Tracey as Jimmy (seasons 1–2, 6; guest seasons 3–5), Calvin's right-hand man, who ends up in prison
David Cubitt (seasons 1–2, 4; guest seasons 3, 5) and Josh Blacker (season 6) as Calvin, the man who ran the illegal pot farm on the other side of Virgin River and the father of Charmaine's twins
Teryl Rothery as Muriel, an actress and a rival of Hope's and a member of Virgin River's knitting circle
Gwynyth Walsh as Jo Ellen, a member of Virgin River's knitting circle who put Mel up while her cabin is renovated
Christina Jastrzembska as Lydie, Ricky's grandmother, a member of Virgin River's knitting circle.
Chase Petriw as Christopher (seasons 1–4; guest season 5), Paige's son who forms a close bond with Preacher
Trevor Lerner as Bert Gordon (seasons 2–present; guest season 1), Virgin River's resident Tow-Truck Driver
Steve Bacic as Wes (season 2; guest seasons 3–5), Paige's estranged abusive husband, and Vince, his identical twin. Michael Shanks also portrayed Wes in season 1.
Keith MacKechnie as Nick (seasons 2–present), Jo Ellen's husband, co-owner of the local BnB and former mayor of Virgin River
Carmel Amit as Jamie (season 2; guest season 6), a restaurant-owner visiting Virgin River who connects with Preacher
Chad Rook as Spencer (season 2; guest season 1), one of Calvin's workers
Patrick Sabongui as Todd Masry (season 3), Charmaine's wealthy fiancé
Lucia Walters as Julia (seasons 3–5), an Aikido teacher that Preacher dated
Stacey Farber as Tara Anderson (seasons 3–5; guest season 6), Lilly's daughter
Clare Filipow as Hannah (seasons 3–present), a server at Jack's Bar
Barbara Pollard as Melissa Montgomery (seasons 4–5), Jo Ellen's sister-in-law, who runs the lumber company
Libby Osler as Ava Anderson (season 5; guest season 6), Lilly's daughter, Tara's sister
Elise Gatien as Lark (seasons 5–6), a woman who befriends Brady
Gabrielle Rose as Amelia Sheridan (season 5–present), Brie and Jack's mother
John Allen Nelson as Everett Reid (guest season 5; recurring season 6–present), Mel's biological father
Callum Kerr as Everett (season 6), Mel's father in the 1970s flashbacks
Jessica Rothe as Sarah Jensen (season 6), Mel's mother in the 1970s flashbacks
Sara Canning as Victoria (season 7), an investigator for the state medical board
Cody Kearsley as Clay (season 7)
Mitchell Slaggert as Eddie (season 8)
Natasha Calis as Dr. Astrid (season 8)
