Weddell is a surname, and may refer to:
Alan Weddell (born 1950), American football player and coach
Alexander W. Weddell (1876–1948), American diplomat
James Weddell (1787–1834), British sailor and polar explorer
John Weddell (1583–1642), English sea captain
Mimi Weddell (1915–2009), American actress
Robert Weddell (1882–1951), Australian soldier and government administrator
William Weddell (1736–1792), English landowner and politician