William Matthews, occasionally spelled Mathews, was an American Catholic priest and college administrator. He was the fifth ordained in the United States and the first born in British America.
- Occupation
- Catholic priest, academic administrator, professor, educator
- Position held
- President of Georgetown University, pastor, vicar apostolic, President of Gonzaga College High School
- Citizenship
- United States
- Born
- December 16, 1770
- Died
- April 30, 1854
