1999 to present
With Gotobed back in the line-up (now using his birth name, Robert Grey), the group initially reworked much of their back catalogue for a performance at Royal Festival Hall in 2000. Wire's reception during a short tour in early May of the US, and a number of UK gigs, convinced the band to continue. Two EPs, Read & Burn 01 and Read & Burn 02 were released in 2002. Seven of the tracks from the two EPs were collected with four previously unreleased tracks on the 2003 album, Send. Wire collaborated with stage designer Es Devlin and artists Jake and Dinos Chapman. In 2005, The Scottish Play: 2004, which contained recordings of live performances from this era, was released.
In 2006, Wire's 1970s albums were remastered and re-released with the original vinyl track listings. In 2007, Read & Burn 03 was released. According to Newman, Gilbert featured in a minimal capacity on this EP; Gilbert would no longer feature in Wire after this release. Later, in 2010, Wire would release Send Ultimate which added a bonus disc to the Send album. Send Ultimate collected all the tracks from the first two Read and Burn EPs along with other unreleased material and both sides of the "Twelve Times You" single. A full-length album of new material entitled Object 47 was released in July 2008 with Wire now consisting of three members.
In January 2011, Wire released Red Barked Tree, which according to the band's press release "rekindles a lyricism sometimes absent from Wire's previous work and reconnects with the live energy of performance, harnessed and channelled from extensive touring over the past few years". The album was written and recorded by Newman, Lewis and Grey, but speaking to Marc Riley on the day of the release, Newman introduced as "a new boy" guitarist Matt Simms (from It Hugs Back), who had been a touring member with the band since April 2010.
In March 2013 the band released Change Becomes Us, their 13th studio album, which was very well received. Their fourteenth album, eponymously titled Wire, was released in April 2015. The following year, in April 2016, the band's 15th studio album, entitled Nocturnal Koreans, was released on their label Pinkflag. The album consisted of eight songs recorded during the sessions for their previous album which were as of then unreleased. Stereogum named Nocturnal Koreans the Album of the Week. Reviews for the album were mostly positive. In 2017 Wire celebrated 40 years since their debut gig on 1 April 1977 by releasing their 16th studio album, Silver/Lead, and headlining the Los Angeles edition of their DRILL : FESTIVAL.
In 2018, Wire released multi-disc special editions of their first three albums. Each album was housed in a book containing lyrics and other information about the album. The three releases collected non-LP singles and the demo sessions from this era along with remastered versions of the original albums. Also in 2018, Wire released a nine-disc vinyl box set, Nine Sevens, which compiled their first eight singles and the free EP given away with 154. Nine Sevens was rereleased in April 2025 as a double vinyl set as part of Record Store Day.
In January 2020, Wire released Mind Hive on their own Pinkflag label. The band appeared on the front cover of Wire magazine (issue 432) published in January 2020; it featured an interview with the band about the new album and discussed the enduring nature of the group.
On Record Store Day, June 2020, Wire released an eight-song album entitled 10:20. Side one of the vinyl LP consists of four tracks that were originally released as the limited edition Strays EP, which was given away with mail ordered copies of Red Barked Trees. Side two contains four tracks that were recorded during the Mind Hive sessions but not released until their appearance on 10:20.
In June 2021, in conjunction with Record Store Day, Wire released PF456 Deluxe an 18-song vinyl-only compilation of the first two Read and Burn EPs, the "Twelve Times You" single, and the four unreleased tracks from Send. Concurrently, Wire released a CD version of PF456 Redux, a 16-song vinyl-only compilation, originally released in 2003, of edited versions of all the songs from the first two Read and Burn EPs along with the unreleased songs on Send.
In April 2022, in conjunction with Record Store Day, Wire released Not About to Die which was originally released as a bootleg in the early 1980s. The album consists of recordings made for EMI as demos for the 1978 and 1979 albums, Chairs Missing and 154. The songs on Not About to Die were also previously released in 2018 by Wire on the special editions of the two EMI albums.