Screen
Redmayne made his screen debut in 1998 in an episode of Animal Ark. His television credits include the BBC miniseries Tess of the d'Urbervilles, the miniseries The Pillars of the Earth, and the two-part miniseries Birdsong. David Chater, who served as a correspondent in many conflict-ridden areas, described his performance as a WWI soldier in Birdsong as "mesmerising", "astonishing", "so little is visible on the surface and yet a whole universe of emotions is simmering away behind those limpid eyes."
Redmayne was cast in his first feature film Like Minds (2006) after being spotted by casting director Lucy Bevan performing in a play called Goats. Redmayne has appeared in films such as The Good Shepherd (2006), Savage Grace (2007), Powder Blue (2008), The Other Boleyn Girl (2008), Glorious 39 (2009), and Hick (2011). He starred as Osmund in Christopher Smith's supernatural gothic chiller film Black Death (2010). His 2008 Sundance drama film The Yellow Handkerchief was released on 26 February 2010 by Samuel Goldwyn Films.
In 2011, Redmayne starred as filmmaker Colin Clark in the drama film My Week with Marilyn. He took on the role of Marius Pontmercy for the 2012 musical film Les Misérables.
In 2014, Redmayne starred as Stephen Hawking in The Theory of Everything, a role for which he won the Academy Award, BAFTA, Golden Globe, and Screen Actors Guild Award for Best Actor, depicting the debilitating challenges of ALS. Hawking was very pleased by the portrayal, stating "I thought Eddie Redmayne portrayed me very well. At times I thought he was me. I think Eddie's commitment will have a big emotional impact." Dr Katie Sidle, a consultant neurologist specialising in the field of motor neurone disease (MND), stated in an interview in the British Medical Journal, "Eddie's performance in the film was utterly remarkable . . . The patients and carers loved the film. They thought it was very relevant to them."
In early 2015, Redmayne appeared in the Wachowski's film, Jupiter Ascending as Balem Abrasax. The film was widely panned, including his performance, and won him the Golden Raspberry Award for Worst Supporting Actor.
In recent years, the film and the performance have been re-evaluated, with Keith Phipps writing that the "film has shown every sign of turning into a full-fledged cult hit." Writing in Vanity Fair in 2018, Laura Bradley remarked that "the idea that this film would have been improved by Redmayne playing his part in a more conventional (read: boring) manner is absurd." In 2022, Joe Hoeffner echoing her thoughts, felt that with a more "normal villain", "the rest of the film would be flatter, less colorful, less deliriously camp...no matter what happens you can't take your eyes off of the spacefaring Oedipus with the voice of a chainsmoker."
Redmayne also presented the 2015 documentary War Art with Eddie Redmayne, made as part of the ITV's Perspectives programme. In 2015, Redmayne guest starred as Ryan the Tank Engine in the Thomas & Friends movie Sodor's Legend of the Lost Treasure.
That same year, Redmayne starred in the biographical drama The Danish Girl, directed by Academy Award-winning director Tom Hooper. In the film, released in the United Kingdom on 1 January 2016, Redmayne portrayed transgender pioneer Lili Elbe, a casting choice that was met with backlash from the transgender community. Nonetheless, Redmayne's performance garnered critical acclaim; in January 2016, he earned his second nomination for the Academy Award for Best Actor in consecutive years. Redmayne later acknowledged the controversy surrounding his casting by stressing the importance of casting transgender people to play transgender characters.
In 2016, Redmayne starred as Newt Scamander in the film adaptation of Fantastic Beasts and Where to Find Them, the first of a series within the Wizarding World of the Harry Potter film series, with a screenplay by J. K. Rowling. Fantastic Beasts was a critical and commercial success. In 2018, Redmayne starred in the stop-motion animated film Early Man, and reprised his role as Newt Scamander in Fantastic Beasts: The Crimes of Grindelwald as well as its third sequel, Fantastic Beasts: The Secrets of Dumbledore, which was released in April 2022. Both The Crimes of Grindelwald and The Secrets of Dumbledore received mixed critical reception but emerged as financial successes. All of J. K. Rowling's Fantastic Beasts films rank among Redmayne's highest-grossing films to date.
In 2020, Redmayne starred as Tom Hayden in The Trial of the Chicago 7. The film earned six nominations at the 93rd Academy Awards. Redmayne received a Screen Actors Guild Award as a member of the cast awarded the Outstanding Performance by a Cast in a Motion Picture honour.
In 2022, Redmayne starred in the biographical crime thriller film, The Good Nurse, playing notorious serial killer Charles Cullen, and was nominated for a Golden Globe Award, a British Academy Film Award, and a Screen Actors Guild Award. Leah Greenblatt at Entertainment Weekly wrote, "an eerie, pitch-perfect Redmayne, wearing Charlie's nice-guy drag like a battering ram, lets his mask slip so incrementally that the final scenes feel like a true terrifying rupture." Aurora Amidon at Paste remarked, "Redmayne plays Charles with such a sense of naturalism and magnetic intensity that it's easy to forget he's not in the room right there with you."
In 2024, he starred in and produced the television series The Day of the Jackal, playing an elusive British assassin code-named the "Jackal". The performance was acclaimed, and he received nominations for a Screen Actor's Guild Award, a Critics Choice Award and a Golden Globe Award. Joel Golby, writing for the Guardian commended Redmayne for playing his "chameleonic and ice-cold" character, and for conveying a lot while having little dialogue; adding that "it's as if he's secretly uncovered a new way of acting". Verne Gay at Newsday remarked, "To the broadest of screen stereotypes - brutal assassin on the run - he adds layer upon layer, nuance upon nuance".